Chunk #11 — 2 Methods — 2.1 LD Hub database — LD score information

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LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.

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We pre-calculated LD scores for each SNP using individuals of European ancestry from the 1000 Genomes project (1000 Genomes Project Consortium, 2012). These LD scores are suitable for standard LD score analyses in European populations (i.e. the LD score regression intercept, heritability, genetic correlation, cross-sex genetic correlation).