et al., 2012; [16] Boschloo et al., 2013) and vice versa ([17] Kandel et al., 1999). Mood disorder may be associated with the course of alcohol problems as well as onset ([18] Crum et al., 2018). Scores on an internalizing scale were correlated with risk for alcohol and other drug use disorders in a prior analysis of the Collaborative Study on the Genetics of Alcoholism (COGA) subjects ([19] Acion et al., 2019).