Chunk #93 — METHODS — Statistical analysis — Polygenic risk scores

Source

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses.

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Where SPi is the score for phenotype Pi, ORPi the odds ratio from the logistic regression of sub-phenotype of interest on SPi as a continuous factor while adjusting for 10 PCs, and μ is the mean and σ the standard deviation.