In the 41 mood disorder candidate genes (see Tables S5 and S6), the lowest P-value (0.000067) was observed in an intron of CACNA1C (calcium channel, voltage-dependent, L type), a gene with strong evidence for association to bipolar disorder.37 For further details, see Table S6. The aggregate analysis did not yield evidence that the distribution of P-values in these genes was more significant than expected by chance.
