Consider the following fictional anecdote. Dr. X plans to submit a grant application involving a complex genetic study and proposes to use a specialized recently published statistical method. For a study of the type Dr. X proposes with effect sizes that she finds plausible in her study, the paper introducing the method reports statistical power for sample sizes of 500 and 1,000 at an α-level of 0.001, but Dr. X is planning to use 750 subjects and an α of 0.0001 and wants to know the power she will have. No publicly available software or simple closed form equations exist to calculate power and Dr. X does not have the wherewithal to program and run extensive computer simulations to determine power. What can she do?
