Here we present results of a GWA case-control study in a stringently selected sample of MD inpatients of a tertiary clinic in Munich, Germany, and matched controls devoid of any lifetime psychiatric diagnoses (N=353/366) recruited for the Munich Antidepressant Response Signature (MARS) study (Hennings et al., 2009; Ising et al., 2009). We performed replication of the results of the GWAS in six additional independent samples of German, Dutch, United Kingdom (U.K.) and African American origin (Binder et al., 2008; Choy et al., 2009; Hofman et al., 2007; Lewis et al., 2010b; Muglia et al., 2008; Rietschel et al., 2010). The herein reported association results are based on an overall sample size of 15,089 unrelated individuals.
