receptors” (NHR) are intracellular proteins responsible for sensing steroid and thyroid hormones and some other signaling molecules. Multiple NHR genes implicated in the current analysis are specifically expressed in liver (e.g., HNF4A, HNF4G) and several others function as thyroid hormone receptors, which have been linked to severity of alcohol craving, consumption and withdrawal (Alfos et al., 1996; Ozsoy et al., 2006).