in AA compared with EA (12% vs. 41%) and the larger variance of BMI in AA populations (e.g. the standard deviation in our study was 6.4 kg/m2 compared with 4.2 kg/m2 in European populations [7] explains the reduce power. Fourth, our functional characterization is based on in silico analyses and requires experimental validation. Finally, the majority of study participants were female and it is unclear how a predominantly female population may have influenced the results.
