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Chunk #18 — Results — Relationship between Childhood Trauma Exposure and Alcohol Dependence Severity in Treatment-Seeking Alcoholics

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Childhood trauma exposure and alcohol dependence severity in adulthood: mediation by emotional abuse severity and neuroticism.
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We conducted follow-up mediation analyses for CTQ total score (R2 = 0.30, p < 0.0001) and emotional abuse (R2 = 0.34, p < 0.0001) using the six subfacets of neuroticism as defined by the NEO-PIR (Supplemental Table 2) and found that, in the case of emotional abuse, the mediating effects of neuroticism are driven primarily by the subfacet labeled as impulsiveness (bootstrapped estimate = 0.07, 95% CI = 0.01, 0.17) (Figure 1b).