The simulated mini-exome data for Genetic Analysis Workshop 17 were derived from the pilot3 study of the 1000 Genomes Project (http://www.1000genomes.org). The data consist of information on 3,205 genes containing 24,487 single-nucleotide polymorphisms (SNPs) on 697 unrelated individuals drawn from 7 population samples. The family data consist of 8 extended pedigrees (varying in size from 73 to 128 individuals), also with a total of 697 individuals. The pedigrees were seeded with 202 founders, who were described as having been drawn at random from the 697 unrelated individuals. Two hundred replicates were provided for both the unrelated individuals data set and the family data set. A noteworthy feature of these data is that the SNP genotypes from replicate to replicate are identical. In other words, for any given individual over all replicates, each person is represented as though he or she is one of 200 monozygotic twins.
