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Chunk #31 — 4.0 A New Hybrid Sandwich Estimator

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Modification of the Sandwich Estimator in Generalized Estimating Equations with Correlated Binary Outcomes in Rare Event and Small Sample Settings.
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An advantage of this strategy is that as long as the model-based estimate of variance is a positive definite matrix, the hybrid sandwich estimator will also be positive definite. Referencing Pan’s version of the sandwich estimator from equation (2) the improvements will change the final version of the Rogers hybrid sandwich estimator VR to generally appear as: