nominal p-values smaller than 5.0e-04 applying the recessive model (tab. 1, fig. 1B and fig. S2). The pairwise r2-values ranged from 0.40 to >0.99 in controls (fig. 2A and fig. S2A) suggesting that all eight SNPs might tag the same underlying causative variant. In fact rs1545843 and rs1031681 can be used as tagging SNPs for the associated variants within this locus in Europeans and fall into two separate bins, with an interbin r-squared of 0.67.
