The Sequence Read Archive (10) is a repository for sequencing data generated from the new generation of sequencers, including the Roche-454 GS and FLX, Illumina Genome Analyzer, Applied Biosystems SOLiD System, Helicos Heliscope and CompleteGenomics platforms. Since its inception in 2007, the SRA has accumulated over 10 Tbp of biological sequence data. The SRA is part of the Entrez search system, and SRA data sets are linked to PubMed, WGS, GEO, Database of Genotypes and Phenotypes (dbGaP) and Projects databases. Sequence read BLAST searches are now offered for transcript and whole genome sequence data sets from 454 Sequencing systems, and regular expression pattern matching against short reads of all types is now possible. A version of the SRA has been deployed behind dbGaP authorized access in order to provide archive services for human sequencing data under usage or privacy restrictions.
