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Chunk #31 — 4. DISCUSSION — 4.1. Mania

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Default mode network abnormalities in bipolar disorder and schizophrenia.
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yes

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The only other study of DMN in bipolar disorder and schizophrenia classified these two conditions using the DMN and a temporal lobe network, and did not compare the DMN between groups (Calhoun et al., 2007). A quantitative assessment revealed weaker DMN increases in the posterior cingulate and bilateral parietal cortices in bipolar disorder as compared with controls, but direct comparison with our data is not possible since bipolar disorder subjects in that study were not in a manic episode.