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Chunk #6 — Methods and Materials — Measures — Psychiatric Diagnoses

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MAOA genotype, maltreatment, and aggressive behavior: the changing impact of genotype at varying levels of trauma.
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As previously described (30), a number of standardized parent- and child-report questionnaires and a semistructured diagnostic interview, the Schedule for Affective Disorders and Schizophrenia for School-Age Children (27), were used to generate child psychiatric diagnoses. Maltreated children were significantly more likely than control subjects to meet criteria for any psychiatric diagnosis (64% vs. 32%, p = .001), PTSD (47% vs. 0%, Fisher’s Exact = 50.4, p < .001), major depression (MDD; 10% vs. 0%, Fisher’s Exact = 4.2, p < .05), and any depressive diagnoses (32% vs.12%, Fisher’s Exact 5.3, p < .02). Although maltreated children were more likely than control subjects to meet criteria for conduct disorder (7% Vs. 0%) and oppositional defiant disorder (8% Vs. 5%), these differences were not statistically significant within the sample of subjects included in this report. Eighteen percent of the sample met criteria for attention-deficit/hyperactivity disorder (ADHD), and there were no differences in rates of this diagnosis in the two groups.