Chunk #80 — Online Methods — Differential Chromatin Accessibility Analysis — Comparison of Differentially Accessible Genes and Differentially Expressed Genes

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Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder.

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For the GSEA analyses, the log2 fold changes from the differential expression analysis were used as the ranks, and genes with at least 1 DAR in the promoter region were used as the gene sets, separated into genes with positive log2 fold changes, and those with negative log2 fold changes.