The primary analyses focused on the reward and positive affect scales of the Profile of Mood States. The analyses involved a 2 (genotype: TT vs CT or CC) × 3 (drink: 1 vs 2 vs 3) repeated-measures ANOVA. The dependent variable was the difference between the alcohol and placebo beverage scores for each drink. Analyses revealed a significant main effect for genotype (F1,69 = 4.27, P <.05) such that individuals with the CT genotype reported significantly greater reward and positive affect after drinking (F1,69 = 6.27, P < .05) (Figure 4A and B).
