Similar results were obtained for the exploratory analysis of withdrawal, severe drinking, and medical/mental health symptoms. For example, both the withdrawal and severe drinking symptoms showed evidence of linkage to chromosome 1p, and the linkage evidence for the severe drinking symptoms was stronger than that observed for the alcohol dependence diagnosis (LOD = 3.08 vs. 1.41). Additionally, the exploratory analyses also yielded novel evidence for linkage not detected for alcohol dependence such as the evidence of linkage to chromosome 19 for the severe drinking symptoms and chromosome 9 for the withdrawal symptoms.
