Two-tailed p-values for individual transcripts were averaged within each of the three groups, and formed the basis for selection of transcripts by group average p-value (GAP) criteria. Transcripts for which one (or more) GAP was ≤0.01 (or ≥0.99) were included to select transcripts strongly decreased (or increased, respectively) in individual groups, while transcripts where one (or more) GAP ≤0.05 (or ≥0.95) and one (or more) GAP ≤0.10 (or ≥0.90) were selected to include transcripts common to any two (or more) groups. Cases DA 17–18 were omitted from Group I GAP for this calculation only as they represented an intermediate between Group I and Group II ( Fig. 1 ).
