The main dependent variables under analysis were total amount of time (seconds and percentage) spent on the sandpaper-lined compartment (CS2) during the location preference test and behavioral responsiveness registered during phase 2 (wall-climbing, locomotion and head-shaking). Percent time spent on the rough-floor compartment measured time on CS2 compared to time spent on the smooth-floor compartment and was calculated by the formula: (total time spent over sandpaper × 100) / (total time spent over sandpaper + total time spent over smooth. Hence, time spent in the neutral compartment was not taken into account.
