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Chunk #23 — Methods — Statistical analysis — Post hoc analyses stratified by ancestry

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Alcohol milestones and internalizing, externalizing, and executive function: longitudinal and polygenic score associations.
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Given that PGS analyses were conducted within each ancestral group (due to poor portability of PGS prediction across ancestries; Martin et al., 2017), phenotypic analyses were repeated in each ancestry group to facilitate comparison across phenotypic and PGS-based models (Supplemental Methods).