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Chunk #21 — Materials and methods — Gene enrichment analysis

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The effect of alcohol on the differential expression of cluster of differentiation 14 gene, associated pathways, and genetic network.
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Genetic correlation analysis was performed on GeneNetwork to identify transcriptional abundance relationships between Cd14 and other genes. Cd14 was compared to all probe sets in the mouse genome. Genes potentially correlated with Cd14 required an expression level greater than baseline 7.0 as well as a significant correlation with Cd14, indicated by the Pearson product correlations value (p < 0.05). Genes meeting these criteria were then selected for further analysis.