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Chunk #53 — RESULTS — Relationship between Movement-Related PAC Dynamics and β Power Dynamics

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Cross-frequency phase-amplitude coupling in repetitive movements in patients with Parkinson's disease.
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In the present study, we also found β power to be reduced at movement onset and during movement in both patients and controls (Fig. 6, A and B, left). Because the strength of β power affects the estimation of phases in the calculation of PAC, we investigated to what degree modulation of PAC by movement transitions can be explained by associated changes in β power. We assessed the modulation of β power in the five periods of a movement cycle in the pressing and slow tapping tasks (Fig. 6, A and B, right). The modulation pattern of β power appeared to be similar to the modulation pattern of PAC in both tasks as reported in the result of dynPAC. A two-way mixed ANOVA with group and period was applied to the β power in pressing and slow tapping tasks. The analysis in the pressing task revealed only a main effect of Period [F(4,148) = 13.18, P < 0.001], while a significant interaction of group and period [F(4,148) = 3.98, P = 0.004] was revealed in the slow tapping task. This