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Chunk #10 — Online methods — Meta-analysis of lung cancer GWAS

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Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
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We combined imputed genotypes from 14,803 cases and 12,262 controls from the OncoArray series with 14,436 cases and 44,188 controls samples undertaken by the previous lung cancer GWAS3,4,6, including studies of IARC, MDACC, SLRI, ICR, Harvard, NCI, Germany and deCODE as described previously3,4,6, and we ensured that there were no overlap between the ATBC, EAGLE and CARET studies included in both the previous GWAS and current OncoArray dataset by comparing the identity tags (IDs) of all study participants.