EnhG), and a state associated with zinc finger protein genes (ZNF/Rpts). The inactive states consist of constitutive heterochromatin (Het), bivalent regulatory states (TssBiv, BivFlnk, EnhBiv), repressed Polycomb states (ReprPC, ReprPCWk), and a quiescent state (Quies) which covers on average 68% of each reference epigenome. Enhancer and promoter states cover approximately 5% of each reference epigenome on average, and show enrichment for evolutionarily-conserved non-coding regions41.
