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Chunk #33 — Figure 2

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Polygenic dissection of major depression clinical heterogeneity.
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Proportions of variance explained on the liability scale for MDD and subtypes (severe typical and severe atypical) by the GPRS for psychiatric and metabolic traits. Explained variance based on R2 coefficient proposed by Lee at al.(39); prevalences for linear transformation into liability scale: MDD K=0.18, severe typical K=0.035, severe atypical K=0.038