Chunk #52 — 3. Impact of spatial scale on CSD implementations — 3.3. Empirical considerations for planar (two-dimensional) scalp-recorded EEG — 3.3.2. CSD as a conservative description of neural current generators
Practical inverse solutions must necessarily be constrained by simplifications of the general model. In addition to structural nuances (e.g., number and geometry of shells or compartments between the neuronal generators and the scalp), dipole inverses require the identification of a set (i.e., one or more) of generator locations with predictable forward solutions (i.e., locations, magnitudes as well as orientations). Even a dipole at a plausible location may be inconsistent with known physiology if it requires an inexplicable orientation.
