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Chunk #13 — Methods — Measures — Substance involvement and psychiatric assessment — Alcohol Milestones/Transitions.

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Alcohol milestones and internalizing, externalizing, and executive function: longitudinal and polygenic score associations.
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Given that age of first intoxication may be a better predictor of mental health outcomes (Newton-Howes, Cook, Martin, Foulds, & Boden, 2019), supplemental analyses defined the origin as first intoxication when predicting first AUD symptom and diagnosis (Supplemental Methods).