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Chunk #28 — Discussion

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Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: a novel transcript fetally regulated by the psychosis risk variant rs1344706.
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on Western blots, it could be subsumed within the approximately 137-kDa band corresponding to full-length ZNF804A if ZNF804AE3E4 undergoes posttranslational modifications that increase its apparent molecular weight. If it is translated, ZNF804AE3E4 may well contribute to the non–transcription factor–related functions postulated here (because it lacks a zinc finger domain), but it does not contain strong sequence motifs or homologies that might give positive clues in this regard.