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Chunk #15 — Results — Distribution of Allele Frequency Differences between Icelandic Subpopulations

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The impact of divergence time on the nature of population structure: an example from Iceland.
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A consequence of these findings is that whenever λ is close to 1 in a disease association study involving the Icelandic population, false positive associations due to population stratification can be conclusively ruled out. If λ is greater than 1, then dividing association statistics by λ will still prevent false positive associations. This is not the case in populations, such as European Americans, with a subtle level of structure arising from more ancient divergence [25].