Chunk #10 — MATERIALS AND METHODS — Statistical analysis

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Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans.

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In secondary analyses, we examined the three low frequency variants (rs2229961, rs80087508, rs79109919) as individual terms along with the common rs16969968 variant and aggregate rare variants (Multivariate Model Set 2). The secondary logistic regression model was logit(p)=β0+βG1rs16969968+βG2rs2229961+βG3rs80087508+βG4rs79109919+βG5RareTerm+βCC.