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Chunk #22 — Results — Neurocognitive Correlates of White Matter Anomalies — Fractional anisotropy

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Neurocognitive correlates of white matter quality in adolescent substance users.
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Regression analyses also revealed important findings in temporal brain regions. FA in the right superior temporal gyrus (β = .30; p<.05) and the right ILF (β = .31; p<.01) predicted performance on WAIS-III Digit Symbol total scaled score in both groups. The group main effects and FA × group interactions were nonsignificant. In addition, a significant FA × group interaction (β = 3.8; p <.05) indicated that increased FA in the right ILF predicted better performance on WAIS-III Digit Span total scaled score for MJ+ALC users (β = .38; p <.05), whereas controls showed no relationship between FA and Digit Span performance (see Figure 1).