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Chunk #36 — Fig. 2

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Differentiation of human pluripotent stem cells into Medial Ganglionic Eminence vs. Caudal Ganglionic Eminence cells.
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FGF8 and FGF19 regulate rostral/caudal identity of ventral telencephalic cells (adapted from [46]). FGF8 treatment induced MGE phenotype while FGF19 induced CGE phenotype, as shown by immunocytochemistry and cell counting analysis after 3 weeks of differentiation of H9 cells (Mean ± SEM; n = 3, P < 0.05, two tailed t-test). The image in the insets is Hoechst-labeled nuclei of the same microscope field. Scale bar: 100 µm.