The PGC has extended its initial efforts in three ways. First, we added four new and highly motivated groups (eating disorders, obsessive-compulsive disorder/Tourette syndrome, post-traumatic stress disorder, and substance use disorders). Provisional groups for anxiety disorders and Alzheimer’s disease have been formed. Second, we hope to markedly increase inclusion of non-European samples (Figure S1). For example, the PGC is now completing a paper based on over 12,000 schizophrenia cases from East Asia. The post-traumatic stress disorder and substance use disorders groups are studying increasingly larger samples of African-Americans. The Stanley Center of the Broad Institute has launched major sample collection efforts for multiple severe psychiatric disorders in Africa, South America, and Asia.
