Faster metabolizers reported greater withdrawal symptoms after 24 hours of abstinence compared with slower metabolizers (see Table 2). These differences remained significant even after adjusting for the number of cigarettes smoked per day (p= .03), the duration of time since beginning to smoke daily (p= .03) and adjusting for time since last cigarette smoked (p=.03). Specifically, faster metabolizers experienced greater levels of insomnia, anger, difficulty concentrating, and impatience as well as total overall withdrawal (p values ranged from .02–.04).
