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Chunk #2 — Introduction

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Clinical, Functional, and Biological Correlates of Cognitive Dimensions in Major Depressive Disorder - Rationale, Design, and Characteristics of the Cognitive Function and Mood Study (CoFaM-Study).
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However, cognitive impairment may not only affect the individual’s ability to function during acute episodes of the illness, as a large body of literature now suggests that cognitive dysfunction may continue into and after remission (6, 29, 30). As shown in a meta-analysis, significant moderate deficits in executive function and attention were found to persist in patients whose depressive symptoms had remitted, indicating that cognitive impairment occurs separately from episodes of depression (27).