Here, we describe our pipeline for merging and imputing the individual GWAS datasets within NHS, NHSII, HPFS and PHS. Datasets were merged based on genotype platform family and all data were subsequently imputed to a common reference panel (the 1,000 Genomes Phase I release [42]). We present proof-of-principle results from genome-wide analysis of body mass index (BMI) and venous thromboembolism (VTE).
