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Chunk #34 — Results — Conditional Models with Peer Group Antisocial Behavior Interacting with CHRM2

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Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior.
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of the nine candidate SNPs (Table 5; odds ratios ranging from 2.6 to 3.6), with a trend toward significance in a seventh SNP (OR = 2.2). In addition, peer group antisocial behavior was useful in distinguishing between genotypic variability in discrete forms of developmentally limited externalizing behavior; that is, adolescents with low versus moderate decreasing trajectories. As shown in Table 5, this finding was confirmed in three SNPs (odds ratios ranging from 1.9 to 4.1), with two additional SNPs yielding marginal associations (OR = 2.0 and 2.5). Again, following a standard Bonferroni correction, the interaction effect remained significant with respect to both contrasts, but only for a single SNP. Again, post-hoc analyses with sex as a covariate revealed a pattern of associations consistent with those described above.