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Chunk #8 — Method — Statistical analyses

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Alcohol consumption in men is influenced by qualitatively different genetic factors in adolescence and adulthood.
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We used a Cholesky decomposition model (six A factors, six C factors, and six E factors) for these analyses, as this structure allows us to impose a temporal structure on the manifest variables (from left to right as time progresses). This enabled us to evaluate whether new latent A (or C) influences ‘ come online’ over time. We compared submodels in which later (epoch 2–6) C and A factor loadings were sequentially removed from the model using the p value of the χ2 and Akaike’s Information Criterion (Akaike, 1987) as an indicator of model fit and parsimony. We did not test the significance of E factor loadings, as such tests were peripheral to our research question and could result in over-fitting. Thus, the structure of E factor loadings remained saturated throughout the model-fitting process.