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Chunk #41 — Results — DNS

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Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis.
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ELS and amygdala habituation (bE = -0.20, 95% CI [-0.28, 0.40], p = .744). Post-hoc Johnson-Neyman tests revealed that the association between genotype and amygdala habituation was significant at mean-centered log-transformed CTQ values of -0.06 (i.e., raw score of 26.68, where the minimum possible score is 25) and below. This pattern is consistent with SAGE, in which, among individuals reporting no CA, A allele carriers had relatively higher cannabis dependence symptoms. The main effects of ELS and genotype on habituation were not significant, and, as in both CATS and SAGE, genotype was not associated with ELS (all ps > 0.10).