Chunk #261 — X. Directions, summary and conclusions

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Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects.

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This work, taken together, supports the idea that the heritable brain bases for individual differences in addiction vulnerability lie squarely in the midst of the repertoire of common complex determinants of individual differences that are manifest in many heritable complex brain disorders and phenotypes. Such conclusions place the biology of addictions squarely in the midst of important biologies of a number of brain phenotypes and disorders, hopefully in ways that will benefit them all.