In all analyses, we evaluated results at a voxelwise threshold of p<.005, combined with a cluster size threshold of 29 contiguous voxels (783 mm3). This combined threshold was estimated with a Monte-Carlo simulation using AlphaSim (Douglas Wand, http://afni.nimh.nih.gov/pub/dist/doc/program_help/AlphaSim.html) to yield an overall threshold of p<.05, corrected for multiple comparison for the whole brain. In the first level analysis, we constructed for each individual the contrast for successful response inhibition SS>GS. In the second level analysis, we conducted a one-sample t test to identify regional activations to response inhibition across all participants and compared drinkers with non-drinkers with small volume correction (SVC) for regions of interests (ROIs).
