METASTROKE brings together GWAS data from most groups working in the area of stroke genetics worldwide. This paper describes the details of every population and represents the first analysis of the datasets. Various additional GWAS studies in stroke are currently taking place or have recently been completed, including a recently published GWAS in an Australian population, which confirmed an association at a 6p21.1 locus with large-artery atherosclerotic stroke.31 The addition of these data might lead to identification of further novel associations with ischaemic stroke.