Chunk #34 — The search for gene variants related to alcohol sensitivity (See Table 1) — Potassium and calcium channel related genes

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A Critical Review of Methods and Results in the Search for Genetic Contributors to Alcohol Sensitivity.

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Animal homologs of human KCNMA1 (chromosome 10q22.3) might relate to the intensity of alcohol responses in Drosophila and C. elegans (Davies et al., 2003; Wang et al., 2001). In humans, a locus on chromosome 10 near KCNMA1 related to low LRs on the SRE (Ehlers et al., 2010; Wilhelmsen et al., 2003). A similar chromosome 10 region related to smoking, and to AUDs (Agrawal et al., 2008; Gelernter et al., 2009; Li et al., 2006).