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Chunk #77 — ONLINE METHODS — Normalization of Gene Expression and Adjustment for Covariates — Technical validation of normalized gene expression levels using qPCR

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Gene expression elucidates functional impact of polygenic risk for schizophrenia.
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of the different measurement methodologies and because, while the samples came from the same subject and brain region, they were drawn independently for the qPCR and RNA-seq experiments. We thus conclude that the genome-wide RNA-seq-based quantification provides good estimates of true gene expression in DLPFC tissue. Voom-normalized log(CPM) are presented by diagnosis and site for GAD1, PVALB, SLC32A1 and SST(Supplementary Fig. 3B).