5–20) again exhibited impaired passive avoidance of a shock at both PND 17 and PND 48, but not at PND 114, and took longer to spontaneously alter their exploratory strategy on a T-maze where the animal would be confined after visiting a particular arm when tested at PND 16 and PND 63 but not at PND 112 (229). Rats exposed prenatally to ethanol (liquid diet, GD 1–20) have fewer cells in layers II and V of the medial prefrontal cortex, which was correlated with poor performance on a reversal learning task in adulthood [>PND 90; Ref. (230)].
