These analyses evaluated how a relatively simple retrospective measure of a genetically influenced phenotype, the low LR to alcohol, operates across sexes and across generations. The results offered support for three of the hypotheses, and demonstrated unpredicted results for the fourth. In these evaluations the SRE continued to relate to heavier drinking and the number of alcohol problems in both men and women in both generations and correlated significantly across first degree relatives. These analyses represent the first extensive comparison of the performance of SRE-T with SRE-5 in the same subjects.
