This study used an educationally and ethnically diverse sample to examine attitudes associated with the willingness to participate in genetic research of psychiatric disorders. Even after controlling for potential confounders, Blacks, Hispanics, and Whites did not differ significantly on willingness to participate in a study, if fully informed of the procedures, risks, and benefits involved. However, the demographic characteristics and attitudes that are associated with willingness to participate were different for each ethnic group. The results suggest that among Blacks and Hispanics, willingness to participate in genetic research is more strongly influenced by perceived concerns or deterrents, rather than perceived benefits. The trend seems to be in the opposite direction for Whites, with the exception of stigma, which follows a similar but weaker pattern as in Blacks and Hispanics. Finally, we find evidence to support the idea that among Blacks, education and youthful age reduces but does not eliminate the impact of mistrust on willingness to participate in psychiatric genetic research.
