Probands reported on the presence of DSM-III-R alcohol abuse and dependence in their parents at T1 using an instrument similar to the Family History Module (FHAM) from the Collaborative Study on the Genetics of Alcoholism (COGA) protocol. The FHAM has a specificity of 98% and a positive predictive value of about 50%, with a positive indication associated with a 13.6 odds ratio of a diagnosis for the relative at interview (Rice et al., 1995).
