Chunk #39 — Using next-generation sequencing to find novel protein-coding and lncRNA genes outside GENCODE

Source

GENCODE: the reference human genome annotation for The ENCODE Project.

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To identify novel coding and noncoding genes represented in RNA-seq data, we studied transcript models reconstructed using Exonerate (Howald et al. 2012) and Scripture (Guttman et al. 2010), based on the high-depth HBM transcriptomic data from 16 tissues made publicly available from Illumina (ArrayExpress accession: E-MTAB-513; ENA archive: ERP000546).